Human ATP-binding cassette transporter TaqMan low-density array: analysis of macrophage differentiation and foam cell formation

DOI to cite this document:: 10.5283/epub.1015

Langmann, Thomas ; Mauerer, Richard ; Schmitz, Gerd

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Date of publication of this fulltext: 05 Aug 2009 13:24

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Abstract

BACKGROUND: ATP-binding cassette (ABC) transporters cause various diseases and regulate many physiologic processes, such as lipid homeostasis, iron transport, and immune mechanisms. Several ABC transporters are involved in bile acid, phospholipid, and sterol transport, and their expression is itself controlled by lipids. In addition, ABC proteins mediate drug export in tumor cells and promote the ...