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Search for malic acid activating enzyme involved in the synthesis of polymalic acid from plasmodia of Physarum polycephalum

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Olickal, Till
Date of publication of this fulltext: 12 Apr 2005 06:48

Abstract (English)

Polymalic acid (PMLA) is an interesting biopolymer, whose physiological activity is not yet fully understood. The progress in the enzymology of polymalate synthesis has been suffered from an inactivation of the synthetic activity during cell lysis. While the PMLA polymerase was not accessible, a malic acid-dependent ATP-PPi-exchange, which was presumed to belong to a partial activity of the ...


Translation of the abstract (German)

Polymalat (PMLA) ist ein interessantes Biopolymer, dessen physiologische Bedeutung noch nicht gut verstanden ist. Erschwert wird die Entschlüsselung der Polymalatsynthese durch den Verlust der Syntheseaktivität während des Zellaufschlusses. Während eine Polymalat-Polymerase also nicht direkt zugänglich war, konnte ein malatabhängiger ATP-PPi-Austausch, welcher Teil der Polymeraseaktivität sein ...


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