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Impedance analysis and single ion channel recordings on pore-suspending lipid bilayers based on highly ordered pore arrays

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Römer, Winfried
Date of publication of this fulltext: 23 Jan 2006 07:37

Abstract (English)

Ion channels are one of the main drug targets and are in the focus of various membrane biosensor applications and drug screening assays. The aim of this thesis was to develop and characterize a novel membrane system suspending highly ordered porous substrates. This hybrid membrane system was supposed to combine the advantages of freestanding and solid supported lipid membranes. While part of the ...


Translation of the abstract (German)

Ionenkanäle stellen eines der Hauptziele für die Medikamentenentwicklung dar und stehen deshalb besonders im Fokus verschiedenster Membranbiosensor-Anwendungen und Medikamenten-Testsystemen. Das Ziel dieser Arbeit war die Entwicklung und Charakterisierung eines neuartigen porenüberspannenden Membransystems, das durch hochgeordnete, siebartige Strukturen stabilisiert wird. Dieses ...


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