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Monitoring and characterization of T-lymphocyte reconstitution after allogeneic stem cell transplantation

URN to cite this document:
urn:nbn:de:bvb:355-opus-6413
Abu-Khader, Ahmad
Date of publication of this fulltext: 03 Jul 2006 07:45


Abstract (English)

After administration of the hematopoietic stem cells inoculum into the eligible patients in the allogeneic setting, many hematopoietic cells reconstitute in the following months to years after transplantation. The reconstituted cells can be pathogen-specific (e.g. cytomegalovirus (CMV)-reactive T cells), leukemia-specific (i.e. graft versus leukemia (GvL) effect) or recipient-specific (e.g. ...

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Translation of the abstract (German)

Die Rekonstitution hematopoetischer Zellen nach allogener Stammzelltransplantation (SCT) kann Monate bis Jahre in Anspruch nehmen. Die wieder hergestellten (rekonstituierten) Zellen können Krankheitserreger-spezifisch (z.B. gegen das Zytomegalievirus (CMV-reaktive T- Zellen), Leukämie-spezifisch (d.h. Transplantat-gegen-Leukämie (GvL)) oder Empfänger-spezifisch sein (z.B. bei der ...

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