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Protein expression and localization of Pigment Epithelium Derived Factor in the central nervous system of the rat during postnatal development

URN to cite this document:
urn:nbn:de:bvb:355-opus-7573
DOI to cite this document:
10.5283/epub.10559
Van Wagenen, Stefanie
Date of publication of this fulltext: 12 Oct 2007 11:55


Abstract (German)

Pigment Epithelium Derived Factor (PEDF) is a 46-50 kDa monomeric glycoprotein. The protein has a unique combination of functions and to date has been described to have antiangiogenic, neuroprotective and antivasopermeability properties, as well as differentiating activity for certain neuronal and tumor cells. Vascular Endothelial Growth Factor (VEGF) and PEDF share many similar activities. Both ...

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Translation of the abstract (German)

Pigment Epithelium Derived Factor (PEDF) ist ein monomerisches, 46-50 kDa großes Glycoprotein und hat eine einmalige Kombination von Eigenschaften. So hat PEDF antiangiogenetische, neuroprotektive und Antivasopermeabilitätsfunktion, und induziert die Differenzierung bestimmter Neurone und Tumorzellen. Vascular Endothelial Growth Factor (VEGF) und PEDF haben viele Gemeinsamkeiten: beide ...

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