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Role of enzymatically modified low-density lipoprotein (E-LDL) on macrophage gene expression

URN to cite this document:
urn:nbn:de:bvb:355-opus-8959
Duong, Quoc Chinh
Date of publication of this fulltext: 13 Dec 2007 12:10


Abstract (English)

Monocyte-derived macrophage gene regulation plays an important role not only in pathogenesis of atherosclerosis but also in many other inflammatory diseases, such as, cirrhosis, rheumatoid arthritis, glomerulosclerosis, pulmonary fibrosis and chronic pancreatitis. In addition, bioactive lipids as derivatives of lysophospholipids have been remarkably evidenced to contribute to many ...

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Translation of the abstract (German)

Genregulation in Makrophagen spielt eine grosse Rolle in der Pathogenese der Atherosklerose und weiteren inflamatorischen Erkrankungen wie Zirrhose, Rheumatoider Arthritis, Glomerulosklerose, Lungenfibrose und chronischer Pankreatitis. Lysophospholipid-Derivate und andere bioaktive Lipide scheinen verschiedene Schritte dieser Erkrankungen zu modulieren. Ein Ziel dieser Arbeit war deshalb die ...

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