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Role of potassium ion channels (K+ channels) on proliferation and development of colonic cancer

Spitzner, Melanie (2008) Role of potassium ion channels (K+ channels) on proliferation and development of colonic cancer. PhD, Universität Regensburg.

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Date of publication of this fulltext: 11 Feb 2008 16:20

Abstract (English)

As shown in the past potassium ion channels (K+ channels) and chloride ion channels (Cl- channels) are important for proliferation and survival of cancer cells. These ion channels are differentially activated in cancer cells compared to normal tissue or cells. The human colonic cancer cell line T84 was used for in vitro studies on K+ channels and the putative Cl- channel Bestrophin 1 (Best1). The ...


Translation of the abstract (German)

Seit einigen Jahren ist bekannt, dass Kaliumionenkanäle und Chloridionenkanäle sehr wichtig für die Zellproliferation und das Überleben von Krebszellen sind. Diese Ionenkanäle weisen eine unterschiedliche Aktivität auf, wenn man normalen Zellen mit Krebszellen vergleicht. Für in vitro Studien an Kaliumionenkanälen und dem mutmaßlichen Chloridionenkanal Bestrophin 1 (Best1) wurde die humane ...


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Item type:Thesis of the University of Regensburg (PhD)
Date:10 February 2008
Referee:Karl (Prof. Dr.) Kunzelmann
Date of exam:16 January 2008
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Karl Kunzelmann
Keywords:Ionenkanal , Spannungskontrollierter Ionenkanal , Proliferation , Dickdarmkrebs , Kaliumkanal , , ion channel , proliferation , colonic cancer
Dewey Decimal Classification:500 Science > 570 Life sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:10708
Owner only: item control page


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