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In vitro and in vivo comparison of two different light sources for topical photodynamic therapy

Babilas, P. ; Kohl, E. ; Maisch, T. ; Bäcker, H. ; Gross, B. ; Branzan, A. L. ; Bäumler, W. ; Landthaler, M. ; Karrer, S. ; Szeimies, R.-M.
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Date of publication of this fulltext: 05 Aug 2009 13:25


Abstract

BACKGROUND: Photodynamic therapy (PDT) with 5-aminolaevulinic acid (ALA) is an effective and safe treatment option for the treatment of actinic keratosis (AK). Incoherent lamps are often used, matching the absorption maxima of ALA. OBJECTIVES: A comparative trial was performed to evaluate the efficacy of recently developed light-emitting diodes (LEDs). METHODS: Human epidermal keratinocytes were ...

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