Go to content
UR Home

Transforming growth factor beta2-induced myofibroblastic differentiation of human retinal pigment epithelial cells: regulation by extracellular matrix proteins and hepatocyte growth factor

DOI to cite this document:
10.5283/epub.1204
Gamulescu, Maria-Andreea ; Chen, Youxin ; He, Shikun ; Spee, Christine ; Jin, Manlin ; Ryan, Stephen J. ; Hinton, David R.
[img]PDF
(486kB) - Repository staff only
Date of publication of this fulltext: 05 Aug 2009 13:25


Abstract

Retinal pigment epithelial (RPE) cells possess the potential to transdifferentiate into myofibroblasts after stimulation with transforming growth factor beta (TGFbeta) and are implicated in the pathogenesis of proliferative vitreoretinopathy. In this study we evaluated how TGFbeta2 and various extracellular matrix (ECM) proteins modulate the transdifferentiation of human fetal retinal pigment ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons