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Solid-phase synthesis of peptide - metal-complex conjugates

Dirscherl, Georg (2009) Solid-phase synthesis of peptide - metal-complex conjugates. PhD, Universität Regensburg.

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Date of publication of this fulltext: 07 Jan 2009 15:22

Abstract (English)

The synthesis of Fmoc protected SAAC and their use in solid-phase synthesis is reported. Peptide � metal complex conjugates were either obtained by incorporation of the metal coordinated SAAC followed by mild nucleophilic resin-cleavage or by complexation in metal salt solution after cleavage from the resin. The reported solid phase peptide synthesis protocols are suitable for automation and the ...


Translation of the abstract (German)

Die Synthese von Fmoc geschützten Amino Säuren mit Chelatliganden und ihre Anwendung in der Festphasensynthese wird berichtet. Peptid � Metallkomplex Konjugate wurden entweder durch Inkorporation von Metall gebundenen, auf Amino Säure basierenden Chelatliganden erhalten, welche dann anschließend unter milden Bedingungen vom Resin abgespalten wurden. Alternativ konnten Peptid � Metallkomplex ...


Export bibliographical data

Item type:Thesis of the University of Regensburg (PhD)
Date:6 January 2009
Referee:Burkhard (Prof. Dr.) König
Date of exam:14 December 2007
Institutions:Chemistry and Pharmacy > Institut für Organische Chemie > Lehrstuhl Prof. Dr. Burkhard König
Keywords:Metallkomplexe , Peptidsynthese , Festphasentechnik , Festphasensynthese , solid-phase peptide synthesis , metal-complex , single amino acid chelate
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:12078
Owner only: item control page


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