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Heat shock proteins in immunity

Multhoff, G. (2006) 172. Heat shock proteins in immunity. In: Gaestel, Matthias, (ed.) Molecular chaperones in health and disease. Handbook of experimental pharmacology, 172 (172). Springer, Berlin, pp. 279-304. ISBN 3-540-25875-2; 978-3-540-25875-9.

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This chapter focuses on immunological effects of eukaryotic and microbial heat shock proteins (HSPs), with molecular weights of about 60, 70, and 90 kDa. The search for tumor-specific antigens resulted in the identification of HSPs. They have been found to elicit a potent anti-cancer immune response mediated by the adoptive and innate immune system. Following receptor-mediated uptake of HSP ...


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Item type:Book section
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number:
16610364PubMed ID
Dewey Decimal Classification:500 Science > 570 Life sciences
600 Technology > 610 Medical sciences Medicine
Created at the University of Regensburg:Yes
Item ID:1215
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