Regulation of polyamine synthesis in human hepatocytes by hepatotrophic factor augmenter of liver regeneration

DOI to cite this document:: 10.5283/epub.1231

Dayoub, Rania

; Thasler, Wolfgang E. ; Bosserhoff, Anja K.

; Singer, Thomas ; Jauch, Karl-Walter ; Schlitt, Hans J. ; Weiss, Thomas S.

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Date of publication of this fulltext: 05 Aug 2009 13:26

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Abstract

Different stages of liver regeneration are regulated by a variety of factors Such as the liver growth associated protein ALR, augmenter of liver regeneration. Furthermore, small molecules like polyamines were proven to be essential for hepatic growth and regeneration. Therefore, using primary human hepatocytes in vitro we investigated the effect of ALR on the biosynthesis of polyamines. We ...