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Rosai-Dorfman disease with cutaneous manifestation (sinus histiocytosis with massive lymphadenopathy)

DOI to cite this document:
Coras, Brigitte ; Michel, Susanne ; Landthaler, Michael ; Hohenleutner, Ulrich
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Date of publication of this fulltext: 05 Aug 2009 13:26


We report a 73-year-old woman with the typical findings of "Rosai-Dorfman disease" (RDD) including massive, painless lymphadenopathy, fever and multiple, asymptomatic cutaneous lesions on her face, collum and neck. Histologically, the lesions were marked by characteristic large macrophages exhibiting emperipolesis.

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