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- URN to cite this document:
- urn:nbn:de:bvb:355-epub-124128
- DOI to cite this document:
- 10.5283/epub.12412
Abstract (German)
Im 3D-Matrixmodell konnte gezeigt werden, dass sich Myofibroblasten aus entzündeter, fistulierter und stenosierter Darmschleimhaut von Morbus Crohn Patienten hinsichtlich Ihrer Migrationspotentiale voneinander unterscheiden. Dies geht ausserdem mit einer unterschiedlichen Expression der Focal Adhesion Kinase (FAK) einher.
Translation of the abstract (English)
Myofibroblasts isolated from inflamed, fibrostenotic or fistulized CD mucosa differ in their migratory potential both in the modified Boyden chamber as well as in a 3D-matrix model. These different migratory behaviours are associated with a different expression of FAK.