Meier, Johannes (2010) Die unterschiedlichen Migrationspotentiale von Myofibroblasten aus entzündeter, fistulierter und stenosierter Darmschleimhaut von Morbus-Crohn-Patienten gehen mit einer unterschiedlichen Expression der Focal Adhesion Kinase (FAK) einher. PhD, Universität Regensburg.
| License: Publishing license for publications including print on demand Download (2MB) |
Abstract (German)
Im 3D-Matrixmodell konnte gezeigt werden, dass sich Myofibroblasten aus entzündeter, fistulierter und stenosierter Darmschleimhaut von Morbus Crohn Patienten hinsichtlich Ihrer Migrationspotentiale voneinander unterscheiden. Dies geht ausserdem mit einer unterschiedlichen Expression der Focal Adhesion Kinase (FAK) einher.
Translation of the abstract (English)
Myofibroblasts isolated from inflamed, fibrostenotic or fistulized CD mucosa differ in their migratory potential both in the modified Boyden chamber as well as in a 3D-matrix model. These different migratory behaviours are associated with a different expression of FAK.
Export bibliographical data
| Item type: | Thesis of the University of Regensburg (PhD) |
|---|---|
| Date: | 18 February 2010 |
| Referee: | Prof. Dr. Dr. Gerhard Rogler and Prof. Dr. Dr. Torsten E. Reichert |
| Date of exam: | 21 January 2010 |
| Institutions: | Medicine > Lehrstuhl für Innere Medizin I |
| Keywords: | Crohn’s disease, fibrosis, strictures, myofibroblasts, migration, wound healing, focal adhesion kinase |
| Dewey Decimal Classification: | 600 Technology > 610 Medical sciences Medicine |
| Status: | Published |
| Refereed: | Yes, this version has been refereed |
| Created at the University of Regensburg: | Yes |
| Item ID: | 12412 |
Download Statistics
Download Statistics