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Regulation of RANTES and ICAM-1 expression in murine mesangial cells

DOI to cite this document:
10.5283/epub.1255
Satriano, J. A. ; Banas, B. ; Luckow, B. ; Nelson, P. ; Schlondorff, D. O.
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Date of publication of this fulltext: 05 Aug 2009 13:26


Abstract

Chemokines and adhesion molecules play a pivotal role in leukocyte infiltration during tissue injury. RANTES (regulated upon activation, normal T cell expressed and secreted) is a monocyte chemoattractant that induces the expression of CD11/CD18 integrins on leukocytes for which intercellular adhesion molecule-1 (ICAM-1) is the ligand. Both RANTES and ICAM-1 can be expressed by mesangial cells ...

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