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Chemokine and chemokine receptor expression in a novel human mesangial cell line

DOI to cite this document:
10.5283/epub.1262
Banas, B. ; Luckow, B. ; Möller, M. ; Klier, C. ; Nelson, P. J. ; Schadde, E. ; Brigl, M. ; Halevy, D. ; Holthöfer, H. ; Reinhart, B. ; Schlöndorff, D.
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Date of publication of this fulltext: 05 Aug 2009 13:26


Abstract

Chemokines are thought to play a pivotal role in mediating the selective migration of leukocytes into sites of tissue injury. The local production of chemokines by mesangial cells (MC) has been linked to inflammatory processes within the glomerulus. To study the chemokine biology of human MC, an immortalized human MC line was generated and then chemokine and chemokine receptor expression was ...

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