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Protein kinase C (PKC) dependent induction of tissue factor (TF) by mesangial cells in response to inflammatory mediators and release during apoptosis

Lang, Detlef, Terstesse, Martin, Dohle, Frank, Bangen, Philip, Banas, Bernhard, Pauels, Hans-Gerd and Heidenreich, Stefan (2002) Protein kinase C (PKC) dependent induction of tissue factor (TF) by mesangial cells in response to inflammatory mediators and release during apoptosis. British journal of pharmacology 137 (7), pp. 1116-1124.

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Abstract

1. In inflammatory kidney diseases procoagulatory activity (PCA) becomes evident. Glomerular fibrin deposits and capillary microthrombi are histopathological hallmarks in most forms of glomerulonephritis. 2. Therefore in this study the expression of tissue factor (TF) as the main inducer of thrombogenesis was examined in cultured human mesangial cells (MC) in response to proinflammatory stimuli ...

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Item type:Article
Date:December 2002
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
12429585PubMed ID
Keywords:Apoptosis, tissue factor, mesangial cell, IL-1, PKC
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:1267
Owner only: item control page

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