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Regulation of glucose transporters in human peritoneal mesothelial cells

Fischereder, Michael ; Schröppel, Bernd ; Wiese, Patrick ; Fink, Monika ; Banas, Bernhard ; Schmidbauer, Stefan ; Schlöndorff, Detlef
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Date of publication of this fulltext: 05 Aug 2009 13:26


Abstract

BACKGROUND: Risk factors for peritoneal fibrosis and mesothelial cell (MsC) injury in CAPD are infections and bioincompatibility of the dialysate, including high glucose concentrations. To study a potential link between dialysate and glucose toxicity in MsC, we investigated the expression of facilitative glucose transporters (GLUT), which could contribute to glucose toxicity. METHODS: After ...

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