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Bacterial CpG-DNA aggravates immune complex glomerulonephritis: role of TLR9-mediated expression of chemokines and chemokine receptors

Anders, Hans-Joachim, Banas, Bernhard, Linde, Yvonne, Weller, Lars, Cohen, Clemens D, Kretzler, Matthias, Martin, Stefan, Vielhauer, Volker, Schlöndorff, Detlef and Gröne, Hermann-Josef (2003) Bacterial CpG-DNA aggravates immune complex glomerulonephritis: role of TLR9-mediated expression of chemokines and chemokine receptors. Journal of the American Society of Nephrology: JASN 14 (2), pp. 317-326.

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Date of publication of this fulltext: 05 Aug 2009 13:26

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Abstract

Immune complex glomerulonephritis (GN) often deteriorates during infection with viruses and bacteria that, in contrast to mammals, have DNA that contains many unmethylated CpG motifs. Balb/c mice with horse apoferritin-induced GN (HAF-GN) were treated with either saline, CpG-oligodeoxynucleotides (ODN), or control GpC-ODN. Only CpG-ODN exacerbated HAF-GN with an increase of glomerular ...

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Item type:Article
Date:February 2003
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
12538732PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:1270
Owner only: item control page

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