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CC chemokine ligand 5/RANTES chemokine antagonists aggravate glomerulonephritis despite reduction of glomerular leukocyte infiltration

Anders, Hans-Joachim, Frink, Michael, Linde, Yvonne, Banas, Bernhard, Wörnle, Markus, Cohen, Clemens D, Vielhauer, Volker, Nelson, Peter J., Gröne, Hermann-Josef and Schlöndorff, Detlef (2003) CC chemokine ligand 5/RANTES chemokine antagonists aggravate glomerulonephritis despite reduction of glomerular leukocyte infiltration. Journal of immunology 170 (11), pp. 5658-5666.

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Abstract

The chemokine CC chemokine ligand (CCL)5/RANTES as well as its respective receptor CCR5 mediate leukocyte infiltration during inflammation and are up-regulated early during the course of glomerulonephritis (GN). We tested the effects of the two CCL5/RANTES blocking analogs, Met-RANTES and amino-oxypentane-RANTES, on the course of horse apoferritin (HAF)-induced GN. HAF-injected control mice had ...

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Item type:Article
Date:1 June 2003
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
ValueType
12759447PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:No
Item ID:1272
Owner only: item control page

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