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Alkylphosphocholines inhibit proliferation of human retinal pigment epithelial cells

Eibl, Kirsten H, Banas, Bernhard, Schoenfeld, Carlo-L, May, Christian A, Neubauer, Aljoscha S, Priglinger, Siegfried, Kampik, Anselm and Welge-Lussen, Ulrich (2003) Alkylphosphocholines inhibit proliferation of human retinal pigment epithelial cells. Investigative ophthalmology and visual science 44 (8), pp. 3556-3561.

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PURPOSE: To investigate the effect and mechanism of action of alkylphosphocholines (APCs) on proliferation of human retinal pigment epithelium (RPE) cells and RPE-mediated collagen matrix contraction in vitro. METHODS: Cultured RPE cells of five human donors were treated with four APCs in the presence of fetal calf serum. Proliferation was assessed by the tetrazolium dye-reduction (MTT) assay and ...


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Item type:Article
Date:August 2003
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
12882807PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:1274
Owner only: item control page


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