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CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis

Segerer, Stephan, Banas, Bernhard, Wörnle, Markus, Schmid, Holger, Cohen, Clemens D, Kretzler, Matthias, Mack, Matthias, Kiss, Eva, Nelson, Peter J, Schlöndorff, Detlef and Gröne, Hermann-Josef (2004) CXCR3 is involved in tubulointerstitial injury in human glomerulonephritis. The American journal of pathology 164 (2), pp. 635-649.

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Chemokines play pivotal roles in the recruitment of inflammatory cells into the kidney. The chemokine receptors CXCR3 and CCR5 are expressed on activated T lymphocytes, and expression of CXCR3 by mesangial cells has been suggested. Detailed description of CXCR3 expression might form a rational basis for use as a diagnostic marker and for therapeutic CXCR3 targeting in human glomerulonephritis. We ...


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Item type:Article
Date:February 2004
Institutions:Medicine > Lehrstuhl für Innere Medizin II
Identification Number:
14742268PubMed ID
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:1279
Owner only: item control page


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