Signaling danger: toll-like receptors and their potential roles in kidney disease

DOI to cite this document:: 10.5283/epub.1284

Anders, Hans-Joachim ; Banas, Bernhard ; Schlöndorff, Detlef

PDF
(393kB) - Repository staff only

Date of publication of this fulltext: 05 Aug 2009 13:27

Alternative links to fulltext:Pubmed

Details

Export bibliographical data

Abstract

Toll-like receptors (TLR) are an emerging family of receptors that recognize pathogen-associated molecular patterns and promote the activation of leukocytes and intrinsic renal cells. Ligands of the TLR include exogenous microbial components such as LPS (TLR4), lipoproteins and peptidoglycans (TLR1, -2, -6), viral RNA (TLR3), bacterial and viral unmethylated cytosin-guanosin dinucleotide ...