Effects of chemokines on proliferation and apoptosis of human mesangial cells

DOI zum Zitieren dieses Dokuments:: 10.5283/epub.1286

Wörnle, Markus ; Schmid, Holger ; Merkle, Monika ; Banas, Bernhard

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Veröffentlichungsdatum dieses Volltextes: 05 Aug 2009 13:27

Alternative Links zum Volltext:Pubmed DOI Verlag

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BACKGROUND: Proliferation and apoptosis of mesangial cells (MC) are important mechanisms during nephrogenesis, for the maintenance of glomerular homeostasis as well as in renal disease and glomerular regeneration. Expression of chemokines and chemokine receptors by intrinsic renal cells, e.g. SLC/CCL21 on podocytes and CCR7 on MC is suggested to play a pivotal role during these processes. ...