Alkylphosphocholines: a new therapeutic option in glaucoma filtration surgery

DOI to cite this document:: 10.5283/epub.1287

Eibl, Kirsten H. ; Banas, Bernhard ; Kook, Daniel ; Ohlmann, Anne V. ; Priglinger, Siegfried ; Kampik, Anselm ; Welge-Luessen, Ulrich C.

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Date of publication of this fulltext: 05 Aug 2009 13:27

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Abstract

PURPOSE: To investigate the effect of alkylphosphocholines (APCs) on human Tenon fibroblast (HTF) proliferation, migration, and cell-mediated collagen gel contraction. METHODS: HTFs were isolated from tissue samples of three patients obtained during surgery and cultured in DMEM and 10% fetal calf serum (FCS). HTFs (passage 3-6) were treated with one APC in different concentrations spanning the ...