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Quantitative gene expression analysis of fractalkine using laser microdissection in biopsies from kidney allografts with acute rejection

Pietrzyk, M. C. ; Banas, B. ; Wolf, K. ; Rümmele, P. ; Woenckhaus, M. ; Hoffmann, U. ; Krämer, B. K. ; Fischereder, M.
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Date of publication of this fulltext: 05 Aug 2009 13:27


Abstract

Percutaneous biopsy of the kidney remains the gold standard to establish a diagnosis in renal diseases. Only semiquantitative assessments of gene expression on biopsies have been possible so far. We studied gene expression of the chemokine fractalkine (FKN) in 12 biopsies from laser microdissected kidney allografts that showed histologic signs of acute rejection and 10 controls. As quantified by ...

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