RANTES gene polymorphisms predict all-cause and cardiac mortality in type 2 diabetes mellitus hemodialysis patients

DOI zum Zitieren dieses Dokuments:: 10.5283/epub.1301

Böger, Carsten A. ; Fischereder, Michael ; Deinzer, Martina ; Aslanidis, Charalampos ; Schmitz, Gerd ; Stubanus, Mike ; Banas, Bernhard ; Krüger, Bernd ; Riegger, Günter A. J. ; Krämer, Bernhard K.

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Veröffentlichungsdatum dieses Volltextes: 05 Aug 2009 13:27

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INTRODUCTION: Patients with type 2 diabetes (DM2) and end stage renal disease (ESRD) have a dismal survival prognosis, mainly due to cardiovascular events. There is sparse data on genetic predictors. Chemokines and their receptors are important in regulating leukocyte influx and activation in atherosclerosis, and functional polymorphisms in the respective genes are associated with cardiovascular ...