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Steroid withdrawal or steroid avoidance in renal transplant recipients: focus on tacrolimus-based immunosuppressive regimens

Krämer, B. K. ; Krüger, B. ; Mack, M. ; Obed, A. ; Banas, B. ; Paczek, L. ; Schlitt, H. J.
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Date of publication of this fulltext: 05 Aug 2009 13:27


Abstract

Steroid-induced adverse effects after transplantation include cosmetic, metabolic, and cardiovascular complications. Steroid withdrawal or avoidance with cyclosporine-based regimens have been hampered by an unacceptably high rate of acute rejections and increased rates of graft loss. Recently the results of several large, randomized trials of steroid withdrawal/avoidance with tacrolimus-based ...

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