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Ultrastructural insights in the interface between generated renal tubules and a polyester interstitium

Minuth, Will W. ; Denk, Lucia ; Meese, Christine ; Rachel, Reinhard ; Roessger, Anne



Abstract

In regenerative medicine, stem/progenitor cells are emerging as potential candidates for the treatment of renal failure. However, the mechanism of regeneration of renal tubules from stem/progenitor cells is not well-elucidated. In this study, a new method was developed for the generation of tubules replacing coating by extracellular matrix proteins. Renal stem/progenitor cells are mounted between ...

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