Go to content
UR Home

Mechanistic studies on monocyte migration into multicellular spheroids of breast tumor origin

Ksiazkiewicz, Magdalena (2010) Mechanistic studies on monocyte migration into multicellular spheroids of breast tumor origin. PhD, Universität Regensburg.

[img]
Preview
License: Publishing license for publications including print on demand
PDF
Download (3MB)
Date of publication of this fulltext: 20 Apr 2010 12:24

Abstract (English)

The majority of invasive-ductal breast tumors develop a desmoplastic reaction. The most abundant stromal host cell type in desmoplastic tumors are fibroblasts. Moreover, invasive ductal breast cancer is characterized by a high MO/MAC content. These immune cells are predominantly located within the fibroblastic stroma surrounding tumor cell islets. The achieved data reveal that 3-D spheroid ...

plus

Translation of the abstract (German)

Invasiv-duktale Mammakarzinome entwickeln häufig eine desmoplastische Reaktion. Der häufigste Zelltyp zwieschen stromal Host Zellen in desmoplastischen Tumoren sind Fibroblasten. Außerdem weisen invasiv-duktale Karzinome einen hohen Monozyten (MO)/Makrophagen(MAC) Anteil auf. Diese Immunzellen finden sich hauptsächlich im von Fibroblasten durchsetzten Stroma, das den Tumorzellen umgibt. Die hier ...

plus


Export bibliographical data



Item type:Thesis of the University of Regensburg (PhD)
Date:20 April 2010
Referee:Prof. Dr. Armin Kurtz
Date of exam:15 March 2010
Institutions:Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Armin Kurtz
Keywords:monocytes, macrophages, fibroblasts, tumor associated fibroblasts, migration, CCL2, chemokines, breast cancer
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:14042
Owner only: item control page

Downloads

Downloads per month over past year

  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons