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Selective sensitivity of chronic myelogenous leukemia cell populations to alkyl-lysophospholipids.

Andreesen, Reinhard ; Modolell, M. ; Munder, P. G.


In order to evaluate the specificity of alkyl-lysophospholipid-induced cell destruction, peripheral blood leukocytes from chronic myelogenous leukemia (CML) patients in chronic phase of the disease as well as in blastic crisis have been separated by density centrifugation. These subpopulations, enriched for the different maturation stages, were tested for their sensitivity to ...


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