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Human macrophages can express the Hodgkin's cell-associated antigen Ki-1 (CD30)

Andreesen, Reinhard ; Brugger, W. ; Löhr, G. W. ; Bross, K. J.



Abstract

The normal precursor of the neoplastic cell in Hodgkin's lymphoma is still unknown. Previous reports on the expression of the Hodgkin's cell-associated antigen Ki-1, CD30, on normal cells have been limited to activated lymphocytes. This study demonstrates, however, that cells of the macrophage lineage also are able to express the Ki-1 antigen. The Ki-1 antigen is absent from normal blood ...

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