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Surface phenotype analysis of human monocyte to macrophage maturation

URN to cite this document:
urn:nbn:de:bvb:355-epub-142515
Andreesen, Reinhard ; Brugger, W. ; Scheibenbogen, C. ; Kreutz, Marina ; Leser, H. G. ; Rehm, A. ; Löhr, G. W.
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Date of publication of this fulltext: 14 Apr 2010 05:40


Abstract

Cells of the mononuclear phagocyte system arise from circulating blood monocytes. Upon emigration from the vasculature, monocytes differentiate into macrophages, a process that monocytes similarly undergo in vitro. We have established primary cultures from elutriated or adherence-purified blood monocytes and analyzed the antigenic modulation during monocyte to macrophage transformation, which ...

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