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Effect of cytokines and lipopolysaccharides on HIV infection of human macrophages

von Briesen, H. ; von Mallinckrodt, C. ; Esser, R. ; Müller, S. ; Becker, K. ; Rübsamen-Waigmann, H. ; Andreesen, Reinhard



Abstract

Human blood-borne monocytes (MO) differentiating into mature macrophages (MAC) were cultured on hydrophobic Teflon membranes. The cells were infected with two different monocytotropic HIV isolates: HIV1D117III obtained from a perinatally infected child, and HIV2D194 obtained from an AIDS patient who suffered exclusively from neurological symptoms. Virus production monitored by reverse ...

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