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Interleukin-8 and neutrophil activation in acute pancreatitis

Gross, V. ; Andreesen, Reinhard ; Leser, H. G. ; Ceska, M. ; Liehl, E. ; Lausen, M. ; Farthmann, E. H. ; Schölmerich, J.



Abstract

It has been suggested that leucocytes play an important role in the pathogenesis of complicated pancreatitis. Indeed, increased plasma concentrations of neutrophil elastase as a marker of neutrophil activation could be detected in patients with a severe course of the disease. Recently, interleukin-8 (IL-8) has been described as a novel neutrophil activating peptide. To determine the role of IL-8 ...

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