Developmental regulation of granulocyte-macrophage colony-stimulating factor production during human monocyte-to-macrophage maturation

URN to cite this document:: urn:nbn:de:bvb:355-epub-142764
DOI to cite this document:: 10.5283/epub.14276

Krause, S. W. ; Kreutz, Marina ; Zenke, G. ; Andreesen, Reinhard

Preview

PDF
(953kB)

Date of publication of this fulltext: 14 Apr 2010 05:21

Alternative links to fulltext:Pubmed

Details

Preview

Export bibliographical data

Abstract

Cells of the macrophage lineage are a major source of various cytokines and hematopoietic growth factors. With regard to the growth factors acting on cells of their own lineage, macrophage colony-stimulating factor (M-CSF) has been proven to be secreted by monocytes (MO) and macrophages (MAC), whereas the production of granulocyte-macrophage colony-stimulating factor (GM-CSF) by human MO/MAC is ...