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Monocyte differentiation and accessory function: different effects on the proliferative responses of an autoreactive T cell clone as compared to alloreactive or antigen-specific T cell lines and primary mixed lymphocyte cultures

URN to cite this document:
urn:nbn:de:bvb:355-epub-142861
DOI to cite this document:
10.5283/epub.14286
Schlesier, M. ; Krause, S. ; Dräger, R. ; Wolff-Vorbeck, G. ; Kreutz, Marina ; Andreesen, Reinhard ; Peter, H. H.
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Date of publication of this fulltext: 14 Apr 2010 05:10


Abstract

An autoreactive T cell clone derived from a patient with reactive arthritis, two alloreactive T cell lines, two antigen-specific T cell lines and allogeneic resting T cells were analyzed for their responses to monocytes and macrophages derived from monocytes by in vitro differentiation. The autoreactive T cell clone strongly proliferated in response to fresh monocytes and to macrophages derived ...

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