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Endothelial apoptosis is induced by serum of patients after cardiopulmonary bypass

Aebert, H. ; Kirchner, S. ; Keyser, A. ; Birnbaum, D. E. ; Holler, E. ; Andreesen, Reinhard ; Eissner, G.


OBJECTIVE: Increased serum levels of a multitude of mediators like interleukins, tumor necrosis factor, elastase, adhesion molecules, and endotoxin have been described following cardiopulmonary bypass (CPB). The biological consequences of this complex response are unclear. METHODS: Serum samples of nine patients scheduled for elective coronary artery bypass grafting were obtained preoperatively ...


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