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Differential expression of the transcription factor NF-kappaB during human mononuclear phagocyte differentiation to macrophages and dendritic cells

Ammon, C., Mondal, K., Andreesen, Reinhard and Krause, S. W. (2000) Differential expression of the transcription factor NF-kappaB during human mononuclear phagocyte differentiation to macrophages and dendritic cells. Biochemical and biophysical research communications 268 (1), pp. 99-105.

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Abstract

An important role for the Rel/NF-kappaB family of transcription factors in the differentiation process of dendritic cells (DC) and macrophages (MAC) was recently suggested by a number of mouse knockout studies but only little information is available for defined populations of human cells. To investigate the role of individual NF-kappaB proteins [p50, p52, p65 (RelA), RelB] in the differentiation ...

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Item type:Article
Date:2000
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number:
ValueType
10652220PubMed ID
10.1006/bbrc.1999.2083DOI
Classification:
NotationType
AnimalsMESH
Base SequenceMESH
Binding Sites/geneticsMESH
Cell Differentiation/physiologyMESH
Cells, CulturedMESH
DNA/metabolismMESH
Dendritic Cells/metabolismMESH
HumansMESH
Lipopolysaccharides/pharmacologyMESH
Macrophages/metabolismMESH
MiceMESH
Monocytes/metabolismMESH
NF-kappa B/metabolismMESH
Phagocytes/metabolismMESH
Protein Structure, QuaternaryMESH
Proto-Oncogene Proteins/metabolismMESH
RNA, Messenger/metabolismMESH
Transcription Factor RelAMESH
Transcription Factor RelBMESH
Transcription Factors/metabolismMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:14336
Owner only: item control page
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