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Dendritic cells for specific cancer immunotherapy

Meidenbauer, N. ; Andreesen, Reinhard ; Mackensen, A.



Abstract

The characterization of tumor-associated antigens recognized by human T lymphocytes in a major histocompatibility complex (MHC)-restricted fashion has opened new possibilities for immunotherapeutic approaches to the treatment of human cancers. Dendritic cells (DC) are professional antigen presenting cells that are well suited to activate T cells toward various antigens, such as tumor-associated ...

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