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Survival and tumor localization of adoptively transferred Melan-A-specific T cells in melanoma patients

Meidenbauer, Norbert, Marienhagen, Joerg, Laumer, Monika, Vogl, Sandra, Heymann, Jana, Andreesen, Reinhard and Mackensen, Andreas (2003) Survival and tumor localization of adoptively transferred Melan-A-specific T cells in melanoma patients. Journal of immunology (Baltimore, Md. : 1950) 170 (4), pp. 2161-9.

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Abstract

Adoptive T cell therapy has been successfully used for treatment of viral and malignant diseases. However, little is known about the fate and trafficking of transferred Ag-specific T cells. Using the tetramer (TM) technology which allows for detection and quantification of Ag-specific CTL, we assessed the frequency of circulating Melan-A-specific CTL in advanced melanoma patients during adoptive ...

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Item type:Article
Date:2003
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number:
ValueType
12574389PubMed ID
Classification:
NotationType
Antigens, NeoplasmMESH
Cell Division/immunologyMESH
Cell LineMESH
Cell Movement/immunologyMESH
Cell Survival/immunologyMESH
Epitopes, T-Lymphocyte/immunologyMESH
HumansMESH
ImmunophenotypingMESH
Immunotherapy, Adoptive/methodsMESH
Indium Radioisotopes/metabolismMESH
Infusions, IntravenousMESH
Liver/metabolismMESH
Lung/metabolismMESH
Lymphocyte ActivationMESH
Melanoma/therapyMESH
Neoplasm Proteins/immunologyMESH
Pilot ProjectsMESH
Spleen/metabolismMESH
T-Lymphocytes, Cytotoxic/transplantationMESH
Tumor Cells, CulturedMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:14417
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