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Long-term results of first-line sequential high-dose etoposide, ifosfamide, and cisplatin chemotherapy plus autologous stem cell support for patients with advanced metastatic germ cell cancer: an extended phase I/II study of the German Testicular Cancer Study Group

Schmoll, H.-J., Kollmannsberger, C., Metzner, B., Hartmann, J. T., Schleucher, N., Schöffski, P., Schleicher, J., Rick, O., Beyer, J., Hossfeld, D., Kanz, L., Berdel, W. E., Andreesen, Reinhard and Bokemeyer, C. (2003) Long-term results of first-line sequential high-dose etoposide, ifosfamide, and cisplatin chemotherapy plus autologous stem cell support for patients with advanced metastatic germ cell cancer: an extended phase I/II study of the German Testicular Cancer Study Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 21 (22), pp. 4083-91.

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Abstract

PURPOSE: Patients with disseminated germ cell cancer and poor prognosis (International Germ Cell Cancer Collaborative Group [IGCCCG] classification) achieve only a 45% to 50% long-term survival by standard chemotherapy. First-line high-dose chemotherapy might be able to improve the result. This analysis reports toxicity and long-term results of a large phase I/II study of sequential high-dose ...

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Item type:Article
Date:2003
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Identification Number:
ValueType
14568986PubMed ID
10.1200/JCO.2003.09.035DOI
Classification:
NotationType
AdolescentMESH
AdultMESH
Antineoplastic Combined Chemotherapy Protocols/adverse effectsMESH
Cisplatin/adverse effectsMESH
Combined Modality TherapyMESH
Disease-Free SurvivalMESH
Etoposide/adverse effectsMESH
Germinoma/therapyMESH
Hematopoietic Stem Cell TransplantationMESH
HumansMESH
Ifosfamide/adverse effectsMESH
MaleMESH
Middle AgedMESH
PrognosisMESH
Survival RateMESH
Testicular Neoplasms/therapyMESH
Time FactorsMESH
Transplantation, AutologousMESH
Treatment OutcomeMESH
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:14420
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