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A multimodal treatment approach including high-dose chemotherapy in very advanced gastric cancer: evidence for control of metastatic disease

Reichle, A. ; Bolder, U. ; Bataille, F. ; Messmann, H. ; Wagner, H. ; Zaiss, M. ; Wild, P. ; Hofstädter, F. ; Andreesen, Reinhard ; Jauch, K.-W.


The present multimodal treatment approach was designed to achieve prolonged tumor control in advanced gastric cancer. A total of 26 patients with stage IV gastric cancer (metastatic disease n=25), ECOG performance status 0-3 and laparoscopically evaluated peritoneal status received a modified EAP schedule to prove chemosensitivity and to mobilize autologous peripheral blood stem cells (aPBSC). ...


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