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Peripheral dendritic cell chimerism in allogeneic hematopoietic stem cell recipients

Pihusch, Markus ; Boeck, Stefan ; Hamann, Moritz ; Pihusch, Verena ; Heller, Tatjana ; Diem, Heinz ; Rolf, Burkhard ; Pihusch, Rudolf ; Andreesen, Reinhard ; Holler, Ernst ; Kolb, Hans-Jochem



Abstract

BACKGROUND: Relapse and graft-versus-host disease (GVHD) represent major causes of morbidity and mortality following allogeneic hematopoietic stem cell transplantation (HSCT). Although leukocyte and T-cell chimerism analyses are performed routinely suggesting a predictive value on the patients outcome, little is known about chimerism of dendritic cells (DC) representing strong initiators of ...

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