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Diagnosis of hepatic veno-occlusive disease by plasminogen activator inhibitor-1 plasma antigen levels: a prospective analysis in 350 allogeneic hematopoietic stem cell recipients

Pihusch, Markus ; Wegner, Holger ; Goehring, Peter ; Salat, Christoph ; Pihusch, Verena ; Hiller, Erhard ; Andreesen, Reinhard ; Kolb, Hans-Jochem ; Holler, Ernst ; Pihusch, Rudolf


BACKGROUND: Veno-occlusive disease (VOD) is one of the most serious complications following allogeneic hematopoietic stem cell transplantation (HSCT) and is associated with a high mortality. We conducted a large trial in order to investigate the value of plasminogen activator inhibitor-1 (PAI-1) plasma antigen levels in VOD patients as PAI-1 has been described as a possible diagnostic marker of ...


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