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Molecular cloning of two west african human immunodeficiency virus type 2 isolates which replicate well on macrophages: a gambian isolate from a case of neurologic acquired immunodeficiency syndrome, and highly divergent Ghanesian isolate

Kühnel, H., Briesen, H.v., Dietrich, U., Adamski, M., Mix, D., Biesert, L., Kreutz, R., Immelmann, A., Henco, K., Meichnser, C., Andreesen, Reinhard, Gelderblom, H. and Rübsamen-Waigmann, H. (1989) Molecular cloning of two west african human immunodeficiency virus type 2 isolates which replicate well on macrophages: a gambian isolate from a case of neurologic acquired immunodeficiency syndrome, and highly divergent Ghanesian isolate. Proceedings of the National Academy of Sciences of the United States of America (PNAS) 86 (7), pp. 2383-2287.

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Other URL: http://www.pnas.org/content/86/7/2383.full.pdf+html


Abstract

Human immunodeficiency virus type 2 (HIV-2)-related viruses were isolated from a Gambian dying of exclusively neurological disease (HIV-2D194) and from an asymptomatic Ghanian (HIV-2D205). Both strains exhibited properties of HIV-1 biological subtype c: they grew slowly and induced few or no syncytia but eventually produced high levels of particle-associated reverse transcriptase in cultures of ...

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Item type:Article
Date:1989
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Unknown
Created at the University of Regensburg:Yes
Item ID:14521
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