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Patterns of donor-type microchimerism after heart transplantation

Schlitt, Hans-Jürgen ; Hundrieser, J. ; Hisanaga, M. ; Uthoff, K. ; Karck, M. ; Wahlers, T. ; Wonigeit, K. ; Pichlmayr, R.


Allogeneic microchimerism of donor-type has been demonstrated in stable patients in the long-term after organ transplantation. We have analysed microchimerism in skin and blood of 47 heart-transplanted patients after transplantation with polymerase-chain-reaction amplification specific for donor HLA-DRB1. Microchimerism was detectable in 50% of the patients in the first 6 months, in 100% between ...


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