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Transmission of donor lymphocytes in clinical lung transplantation

Richter, N. ; Raddatz, G. ; Steinhoff, G. ; Schäfers, H. J. ; Schlitt, Hans-Jürgen


Passenger mononuclear cells in organ grafts are known to influence the alloimmune response to the graft. To assess their relevance in clinical lung transplantation, we studied the amount, distribution, cell types, and surface marker expression of mononuclear cells in human donor lungs. Two major compartments of mononuclear cells could be differentiated: lymph nodes containing resting T and B ...


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