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Intracavitary doxorubicin hydrochloride therapy for carcinoma in situ of the bladder

Jakse, G. ; Hofstädter, Ferdinand ; Marberger, H.


We treated 15 patients with carcinoma in situ of the bladder by intravesical instillation of doxorubicin hydrochloride. Different dose and interval schedules, that is 40 mg. biweekly and 80 mg. monthly, each resulted in a 66 per cent tumor remission rate. In no instance were undue systemic effects noted; the local side effects were negligible. Cold cup random biopsies were obtained before and ...


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