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Mechanisms of action of intravesical treatment. Effect on the ABH surface antigens of urothelial cells

Jakse, G. ; Hofstädter, Ferdinand


Blood group isoantigens can be demonstrated immune-histologically on normal urothelium of the urinaty bladder by means of the specific red cell adherence test. In preneoplastic and reactive changes of the urothelium and in dysplasia and carcinoma in situ, there is a loss of these antigens. Ultrastructural investigations of carcinoma in situ demonstrate a loss of normal membrane structures such as ...


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